Individuals with mutations in the LMNA gene usually present with dilated cardiomyopathy, atrioventricular block and/or various types of myopathy, and almost half die suddenly. Pasotti and colleagues ...

Sickle cell disease (SCD) altered CD8+ T-cell chromatin architecture, triggering ferroptosis and weakening antitumor immunity. Hydrogen sulfide (H2S) treatment restored chromatin interactions and ...